http://www.guardianunlimited.co.uk/business/story/0,3604,338478,00.html The Guardian Attacks force out biotech guru Andrew Clark Saturday July 1, 2000 One of the most influential financiers behind Britain's biotech industry, Jeremy Curnock Cook, has resigned as head of Rothschild's International Biotechnology Trust amid a growing storm over his personal interest in some of the fund's investments. Mr Curnock Cook, 50, left yesterday "on medical advice" in the middle of a battle for control with a US firm, Millennium Partners. He said that he was "irritated" at "specious personal attacks" from the American company, which he believes have aggravated his long-term heart condition. "There is nothing hidden here - it is a simple issue," said Mr Curnock Cook. "They are choosing to personalise matters with an attack which I think is unneccessary." Millennium, a 10% shareholder, wants to liquidate the #290m fund and distribute the proceeds to investors. It wrote to shareholders last week accusing Mr Curnock Cook of a conflict of interests, after discovering that he held share options worth more than $750,000 in two of the biotech companies in which IBT has invested. IBT said that after a review of the situation, Mr Curnock Cook had agreed to give any profits from his options back to the trust. Mr Curnock Cook said: "It was always my view that the value of the share options would go through to the trust. This was never, for me, an issue. " The options, in the US firms Sugen and Cell Therapeutics, have exploded in value amid a resurgence in the performance of the drug development sector. Mr Curnock Cook was granted the options because he is a non-executive director of the two companies. Corporate governance guidelines in the US - unlike those in Britain - permit such awards to independent directors. Mr Curnock Cook's options have never been disclosed to IBT's shareholders. According to filings with the US Securities and Exchange Commission, he holds options in several other firms in which IBT has invested, including Targeted Genetics and Ribozyme - but their value is unclear. Mr Curnock Cook insisted his resignation from IBT had nothing to do with these disclosures: "My health has been troubling me for a while. One eventually listens to the very good advice one's been given. If you continue to roar around the place, you risk bits falling off." Millennium wants to break up IBT because its share price, which fell 3.5p to 254p yesterday, is well below the total value of its investments - 313p a share. IBT argues that this is because some of its stakes are in early stage, unquoted companies, which cannot easily be cashed in. Mr Curnock Cook said: "Fairly predictably, if an arbitrageur wishes to undermine an investment trust, its first approach has to be to attack the management." A qualified microbiologist, Mr Curnock Cook is an ubiquitous figure in the drug development industry. He is the chairman of Biocompatibles, deputy chairman of Vernalis and also a director of Cantab Pharmaceuticals. Millennium has asked how he can devote attention to IBT when he sits on the board of 23 different companies. Mr Curnock Cook says that some are dormant, and that the true figure is in the "mid-teens". Shareholders will vote on whether to break up IBT at a meeting next Friday. AstraZeneca is one of the biggest investors, with 7%.