CHEMICAL GIANT PAID STUDENTS TO DRINK PESTICIDES: U.S. SEEKS REASONS WHY HUMANS USED TO TEST TOXIN LABELLED 'HIGHLY HAZARDOUS' Bayer CropScience, of Monheim, Germany. one of the world's biggest chemicals companies, faces an inquiry after it was found to have used students to test a "highly hazardous" pesticide linked to serious disorders. The story says that the company paid students, mostly from Heriot-Watt University in Edinburgh, $1,100 each to consume fruit juice laced with the pesticide. The project, the fine detail of which is secret, has been condemned in the U.S. as unscientific and unethical. Lawyers point out that the Nuremberg Code, formulated after the Nazis' wartime experiments, bans the use of humans for testing poisonous substances that have no medical application. Bayer is the daughter company of IG Farben, the manufacturer of Zyklon B, the gas used in Nazi extermination camps. Bayer is using the results of the study, conducted between 1998 and 2000, to support an argument that restrictions on pesticide use should be eased, because no immediate adverse effects were suffered. The story says that groups of up to 16 volunteers were housed at a privately run research centre in Edinburgh and fed azinphos-methyl (AM), an organophosphate chemical. The dosages have not been disclosed. The World Health Organization has classified AM as "highly hazardous." Exposure to it is linked to blood and nervous system problems. The dangers are well documented. Accidental ingestion by 42 Peruvian children last year led to 24 deaths, and recent spillages of the chemical into rivers in Prince Edward Island have killed 15,000 fish. The story adds that although Bayer has not checked on the subsequent health of its human guinea pigs, it is using the research to try to persuade the American Environmental Protection Agency to raise the levels of AM it allows farmers to use on crops. The agency is concerned about the conduct of the studies and has referred them to an expert panel of the respected National Academy of Sciences (NAS). The panel is demanding to know exactly how the unpublished trial was conducted. The agency said last week that 10 of 17 studies it is examining are in Britain and involve Inveresk, a contract research company "The NAS has until December to give an opinion on whether these human studies are ethically and scientifically valid," an agency spokesman said. Nobody from Inveresk was available for comment yesterday. Bayer said its studies were performed "in full accordance with national and international regulations and standards." January 12, 2003, The Ottawa Citizen Lois Rogers, Source: The Times, London